Cerebrospinal fluid immunoglobulin light chain ratios predict disease progression in multiple sclerosis

OBJECTIVE: To determine whether the ratio of cerebrospinal fluid (CSF) immunoglobulin kappa to lambda light chains at time of multiple sclerosis (MS) diagnosis predicts disease progression and whether this was intrinsic to CSF plasmablasts. METHODS: CSF and peripheral blood were obtained from patien...

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Detalles Bibliográficos
Autores principales: Rathbone, Emma, Durant, Lindsay, Kinsella, James, Parker, Antony R, Hassan-Smith, Ghaniah, Douglas, Michael R, Curnow, S John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Multiple Sclerosis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166608/
https://www.ncbi.nlm.nih.gov/pubmed/29743290
http://dx.doi.org/10.1136/jnnp-2018-317947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166608/
https://www.ncbi.nlm.nih.gov/pubmed/29743290
http://dx.doi.org/10.1136/jnnp-2018-317947

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