Rapamycin as an Adjunctive Therapy for NLRC4 Associated Macrophage Activation Syndrome

Gain of function (GOF) mutations affecting the inflammasome component NLRC4 are known to cause early-onset macrophage activation syndrome (MAS) and neonatal enterocolitis. Here we report a patient with a NLRC4 GOF mutation presenting with neonatal MAS efficiently treated with a combination of anakin...

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Detalles Bibliográficos
Autores principales: Barsalou, Julie, Blincoe, Annaliesse, Fernandez, Isabel, Dal-Soglio, Dorothée, Marchitto, Lorie, Selleri, Silvia, Haddad, Elie, Benyoucef, Aissa, Touzot, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166634/
https://www.ncbi.nlm.nih.gov/pubmed/30319625
http://dx.doi.org/10.3389/fimmu.2018.02162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166634/
https://www.ncbi.nlm.nih.gov/pubmed/30319625
http://dx.doi.org/10.3389/fimmu.2018.02162

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