Cargando…
Rapamycin as an Adjunctive Therapy for NLRC4 Associated Macrophage Activation Syndrome
Gain of function (GOF) mutations affecting the inflammasome component NLRC4 are known to cause early-onset macrophage activation syndrome (MAS) and neonatal enterocolitis. Here we report a patient with a NLRC4 GOF mutation presenting with neonatal MAS efficiently treated with a combination of anakin...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166634/ https://www.ncbi.nlm.nih.gov/pubmed/30319625 http://dx.doi.org/10.3389/fimmu.2018.02162 |