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Hydrophobically modified chitosan nanoliposomes for intestinal drug delivery

BACKGROUND: Encapsulation of hydrophilic drugs within liposomes can be challenging. METHODS: A novel chitosan derivative, O-palmitoyl chitosan (OPC) was synthesized from chitosan and palmitoyl chloride using methane-sulfonic acid as a solvent. The success of synthesis was confirmed by Fourier transf...

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Detalles Bibliográficos
Autores principales: Zariwala, M Gulrez, Bendre, Harshada, Markiv, Anatoliy, Farnaud, Sebastien, Renshaw, Derek, Taylor, Kevin MG, Somavarapu, Satyanarayana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166747/
https://www.ncbi.nlm.nih.gov/pubmed/30310283
http://dx.doi.org/10.2147/IJN.S166901