Integrated pharmacokinetic–pharmacodynamic modeling to evaluate empiric carbapenem therapy in bloodstream infections

OBJECTIVES: Treatment for nosocomial bloodstream infections (BSI) caused by multidrug-resistant (MDR) Gram-negative bacteria (GNB) is challenging. Rising antimicrobial resistance, especially in extended spectrum beta-lactamase production, inadvertently increases empiric carbapenem consumption. Three...

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Detalles Bibliográficos
Autores principales: Lim, Tze-Peng, Wang, Reyna, Poh, Gang Quan, Koh, Tse-Hsien, Tan, Thean-Yen, Lee, Winnie, Teo, Jocelyn Qi-Min, Cai, Yiying, Tan, Thuan-Tong, Ee, Pui Lai Rachel, Kwa, Andrea L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166767/
https://www.ncbi.nlm.nih.gov/pubmed/30310294
http://dx.doi.org/10.2147/IDR.S168191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166767/
https://www.ncbi.nlm.nih.gov/pubmed/30310294
http://dx.doi.org/10.2147/IDR.S168191

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