Cargando…

Entropic Control of an Excited Folded-Like Conformation in a Disordered Protein Ensemble

Many intrinsically disordered proteins switch between unfolded and folded-like forms in the presence of their binding partner. The possibility of a pre-equilibrium between the two macrostates is challenging to discern given the complex conformational landscape. Here, we show that CytR, a disordered...

Descripción completa

Detalles Bibliográficos
Autores principales: Munshi, Sneha, Rajendran, Divya, Naganathan, Athi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166778/
https://www.ncbi.nlm.nih.gov/pubmed/29885328
http://dx.doi.org/10.1016/j.jmb.2018.06.008