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Entropic Control of an Excited Folded-Like Conformation in a Disordered Protein Ensemble
Many intrinsically disordered proteins switch between unfolded and folded-like forms in the presence of their binding partner. The possibility of a pre-equilibrium between the two macrostates is challenging to discern given the complex conformational landscape. Here, we show that CytR, a disordered...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166778/ https://www.ncbi.nlm.nih.gov/pubmed/29885328 http://dx.doi.org/10.1016/j.jmb.2018.06.008 |