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Superoxide dismutase activity confers (p)ppGpp-mediated antibiotic tolerance to stationary-phase Pseudomonas aeruginosa

Metabolically quiescent bacteria represent a large proportion of those in natural and host environments, and they are often refractory to antibiotic treatment. Such drug tolerance is also observed in the laboratory during stationary phase, when bacteria face stress and starvation-induced growth arre...

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Detalles Bibliográficos
Autores principales: Martins, Dorival, McKay, Geoffrey, Sampathkumar, Gowthami, Khakimova, Malika, English, Ann M., Nguyen, Dao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166797/
https://www.ncbi.nlm.nih.gov/pubmed/30201715
http://dx.doi.org/10.1073/pnas.1804525115