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Superoxide dismutase activity confers (p)ppGpp-mediated antibiotic tolerance to stationary-phase Pseudomonas aeruginosa
Metabolically quiescent bacteria represent a large proportion of those in natural and host environments, and they are often refractory to antibiotic treatment. Such drug tolerance is also observed in the laboratory during stationary phase, when bacteria face stress and starvation-induced growth arre...
Autores principales: | Martins, Dorival, McKay, Geoffrey, Sampathkumar, Gowthami, Khakimova, Malika, English, Ann M., Nguyen, Dao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166797/ https://www.ncbi.nlm.nih.gov/pubmed/30201715 http://dx.doi.org/10.1073/pnas.1804525115 |
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