Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor

Murine norovirus (MNoV) is closely related to human norovirus (HNoV), an infectious agent responsible for acute gastroenteritis worldwide. Here we report the X-ray crystal structure of the dimeric MNoV VP1 protruding (P) domain in complex with its cellular receptor CD300lf. CD300lf binds the P domai...

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Detalles Bibliográficos
Autores principales: Nelson, Christopher A., Wilen, Craig B., Dai, Ya-Nan, Orchard, Robert C., Kim, Arthur S., Stegeman, Roderick A., Hsieh, Leon L., Smith, Thomas J., Virgin, Herbert W., Fremont, Daved H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166816/
https://www.ncbi.nlm.nih.gov/pubmed/30194229
http://dx.doi.org/10.1073/pnas.1805797115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166816/
https://www.ncbi.nlm.nih.gov/pubmed/30194229
http://dx.doi.org/10.1073/pnas.1805797115

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