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Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis

The Xenopus laevis embryo has been subjected to almost saturating screens for molecules specifically expressed in dorsal Spemann organizer tissue. In this study, we performed high-throughput RNA sequencing of ectodermal explants, called animal caps, which normally give rise to epidermis. We analyzed...

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Detalles Bibliográficos
Autores principales: Ding, Yi, Colozza, Gabriele, Sosa, Eric A., Moriyama, Yuki, Rundle, Samantha, Salwinski, Lukasz, De Robertis, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166843/
https://www.ncbi.nlm.nih.gov/pubmed/30209221
http://dx.doi.org/10.1073/pnas.1812117115