Pharmacogenetic variation influences sensory neuropathy occurrence in Southern Africans treated with stavudine-containing antiretroviral therapy

BACKGROUND: The use of the HIV antiretroviral drug stavudine (d4T), a thymidine analogue, is associated with the development of mitochondrial toxicities such as sensory neuropathy (SN). Genetic variation in genes relating to d4T transport and metabolism, as well as genetic variation in the thymidine...

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Detalles Bibliográficos
Autores principales: Moketla, Marvin Blessings, Wadley, Antonia L., Kamerman, Peter, de Assis Rosa, Debra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166924/
https://www.ncbi.nlm.nih.gov/pubmed/30273369
http://dx.doi.org/10.1371/journal.pone.0204111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166924/
https://www.ncbi.nlm.nih.gov/pubmed/30273369
http://dx.doi.org/10.1371/journal.pone.0204111

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