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MRI-guided intracerebral convection-enhanced injection of gliotoxins to induce focal demyelination in swine
Demyelinating disorders such as multiple sclerosis (MS) or transverse myelitis are devastating neurological conditions with no effective cure. Prevention of myelin loss or restoration of myelin are key for successful therapy. To investigate the disease and develop cures animal models with good clini...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166947/ https://www.ncbi.nlm.nih.gov/pubmed/30273376 http://dx.doi.org/10.1371/journal.pone.0204650 |