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Balancing selection on a recessive lethal deletion with pleiotropic effects on two neighboring genes in the porcine genome

Livestock populations can be used to study recessive defects caused by deleterious alleles. The frequency of deleterious alleles including recessive lethal alleles can stay at high or moderate frequency within a population, especially if recessive lethal alleles exhibit an advantage for favourable t...

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Detalles Bibliográficos
Autores principales: Derks, Martijn F. L., Lopes, Marcos S., Bosse, Mirte, Madsen, Ole, Dibbits, Bert, Harlizius, Barbara, Groenen, Martien A. M., Megens, Hendrik-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166978/
https://www.ncbi.nlm.nih.gov/pubmed/30231021
http://dx.doi.org/10.1371/journal.pgen.1007661