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Balancing selection on a recessive lethal deletion with pleiotropic effects on two neighboring genes in the porcine genome
Livestock populations can be used to study recessive defects caused by deleterious alleles. The frequency of deleterious alleles including recessive lethal alleles can stay at high or moderate frequency within a population, especially if recessive lethal alleles exhibit an advantage for favourable t...
Autores principales: | Derks, Martijn F. L., Lopes, Marcos S., Bosse, Mirte, Madsen, Ole, Dibbits, Bert, Harlizius, Barbara, Groenen, Martien A. M., Megens, Hendrik-Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166978/ https://www.ncbi.nlm.nih.gov/pubmed/30231021 http://dx.doi.org/10.1371/journal.pgen.1007661 |
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