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Crystal structure of a soluble fragment of poliovirus 2C(ATPase)

Poliovirus (PV) 2C(ATPase) is the most studied 2C protein in the Picornaviridae family. It is involved in RNA replication, encapsidation and uncoating and many inhibitors have been found that target PV 2C(ATPase). Despite numerous investigations to characterize its functions, a high-resolution struc...

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Detalles Bibliográficos
Autores principales: Guan, Hongxin, Tian, Juan, Zhang, Chu, Qin, Bo, Cui, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166989/
https://www.ncbi.nlm.nih.gov/pubmed/30231078
http://dx.doi.org/10.1371/journal.ppat.1007304