Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis

Necrotizing enterocolitis (NEC) remains the leading cause of gastrointestinal morbidity and mortality in premature infants. Human and animal studies suggest a role for Paneth cells in NEC pathogenesis. Paneth cells play critical roles in host-microbial interactions and epithelial homeostasis. The ra...

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Detalles Bibliográficos
Autores principales: Lueschow, Shiloh R., Stumphy, Jessica, Gong, Huiyu, Kern, Stacy L., Elgin, Timothy G., Underwood, Mark A., Kalanetra, Karen M., Mills, David A., Wong, Melissa H., Meyerholz, David K., Good, Misty, McElroy, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166990/
https://www.ncbi.nlm.nih.gov/pubmed/30273395
http://dx.doi.org/10.1371/journal.pone.0204967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166990/
https://www.ncbi.nlm.nih.gov/pubmed/30273395
http://dx.doi.org/10.1371/journal.pone.0204967

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