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KChIP3 coupled to Ca(2+) oscillations exerts a tonic brake on baseline mucin release in the colon
Regulated mucin secretion from specialized goblet cells by exogenous agonist-dependent (stimulated) and -independent (baseline) manner is essential for the function of the epithelial lining. Over extended periods, baseline release of mucin can exceed quantities released by stimulated secretion, yet...
Autores principales: | Cantero-Recasens, Gerard, Butnaru, Cristian M, Valverde, Miguel A, Naranjo, José R, Brouwers, Nathalie, Malhotra, Vivek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167051/ https://www.ncbi.nlm.nih.gov/pubmed/30272559 http://dx.doi.org/10.7554/eLife.39729 |
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