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Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice

White adipose tissue (WAT) remodeling is dictated by coordinated interactions between adipocytes and resident stromal-vascular cells; however, the functional heterogeneity of adipose stromal cells has remained unresolved. We combined single-cell RNA-sequencing and FACS to identify and isolate functi...

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Detalles Bibliográficos
Autores principales: Hepler, Chelsea, Shan, Bo, Zhang, Qianbin, Henry, Gervaise H, Shao, Mengle, Vishvanath, Lavanya, Ghaben, Alexandra L, Mobley, Angela B, Strand, Douglas, Hon, Gary C, Gupta, Rana K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167054/
https://www.ncbi.nlm.nih.gov/pubmed/30265241
http://dx.doi.org/10.7554/eLife.39636