Computer Simulation of Multi-Color Brainbow Staining and Clonal Evolution of B Cells in Germinal Centers

Clonal evolution of B cells in germinal centers (GCs) is central to affinity maturation of antibodies in response to pathogens. Permanent or tamoxifen-induced multi-color recombination of B cells based on the brainbow allele allows monitoring the degree of color dominance in the course of the GC rea...

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Detalles Bibliográficos
Autores principales: Meyer-Hermann, Michael, Binder, Sebastian C., Mesin, Luka, Victora, Gabriel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167470/
https://www.ncbi.nlm.nih.gov/pubmed/30319600
http://dx.doi.org/10.3389/fimmu.2018.02020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167470/
https://www.ncbi.nlm.nih.gov/pubmed/30319600
http://dx.doi.org/10.3389/fimmu.2018.02020

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