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pH-Responsive Cross-Linked Low Molecular Weight Polyethylenimine as an Efficient Gene Vector for Delivery of Plasmid DNA Encoding Anti-VEGF-shRNA for Tumor Treatment

RNA interference (RNAi) is a biological process through which gene expression can be inhibited by RNA molecules with high selectivity and specificity, providing a promising tool for tumor treatment. Two types of molecules are often applied to inactivate target gene expression: synthetic double stran...

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Detalles Bibliográficos
Autores principales: Li, Xiaoming, Guo, Xiaoshuang, Cheng, Yuan, Zhao, Xiaotian, Fang, Zhiwei, Luo, Yanli, Xia, Shujun, Feng, Yun, Chen, Jianjun, Yuan, Wei-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167493/
https://www.ncbi.nlm.nih.gov/pubmed/30319959
http://dx.doi.org/10.3389/fonc.2018.00354