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A small molecule inhibitor of the perinucleolar compartment, ML246, attenuates growth and spread of ovarian cancer

BACKGROUND: Ovarian cancer remains a major health problem for women as it is often diagnosed at a late stage with metastatic disease. There are limited therapeutic agents and survival rates remain poor. The perinucleolar compartment (PNC) has been shown to be associated with malignancy and is consid...

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Detalles Bibliográficos
Autores principales: Kanis, Margaux J., Qiang, Wenan, Pineda, Mario, Maniar, Kruti P., Kim, J. Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167785/
https://www.ncbi.nlm.nih.gov/pubmed/30305911
http://dx.doi.org/10.1186/s40661-018-0064-2