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A small molecule inhibitor of the perinucleolar compartment, ML246, attenuates growth and spread of ovarian cancer
BACKGROUND: Ovarian cancer remains a major health problem for women as it is often diagnosed at a late stage with metastatic disease. There are limited therapeutic agents and survival rates remain poor. The perinucleolar compartment (PNC) has been shown to be associated with malignancy and is consid...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167785/ https://www.ncbi.nlm.nih.gov/pubmed/30305911 http://dx.doi.org/10.1186/s40661-018-0064-2 |