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Breast cancer survival predicted by TP53 mutation status differs markedly depending on treatment

BACKGROUND: Previous studies on the role of TP53 mutation in breast cancer treatment response and survival are contradictory and inconclusive, limited by the use of different endpoints to determine clinical significance and by small sample sizes that prohibit stratification by treatment. METHODS: We...

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Detalles Bibliográficos
Autores principales: Ungerleider, Nathan A., Rao, Sonia G., Shahbandi, Ashkan, Yee, Douglas, Niu, Tianhua, Frey, Wesley D., Jackson, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167800/
https://www.ncbi.nlm.nih.gov/pubmed/30285883
http://dx.doi.org/10.1186/s13058-018-1044-5