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Enhanced efficacy of histone deacetylase inhibitor combined with bromodomain inhibitor in glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common and most malignant primary brain cancer in adults. Despite multimodality treatment, the prognosis is still poor. Therefore, further work is urgently required to discover novel therapeutic strategies for GBM treatment. METHODS: The synergistic effects...

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Detalles Bibliográficos
Autores principales: Meng, Wei, Wang, Baocheng, Mao, Weiwei, Wang, Jiajia, Zhao, Yang, Li, Qifeng, Zhang, Chenran, Tang, Yujie, Ma, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167847/
https://www.ncbi.nlm.nih.gov/pubmed/30285808
http://dx.doi.org/10.1186/s13046-018-0916-y