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Impact of ZBTB7A hypomethylation and expression patterns on treatment response to hydroxyurea
BACKGROUND: We aimed to clarify the emerging epigenetic landscape in a group of genes classified as “modifier genes” of the β-type globin genes (HBB cluster), known to operate in trans to accomplish the two natural developmental switches in globin expression, from embryonic to fetal during the first...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167880/ https://www.ncbi.nlm.nih.gov/pubmed/30285874 http://dx.doi.org/10.1186/s40246-018-0177-z |