Cargando…

Impact of ZBTB7A hypomethylation and expression patterns on treatment response to hydroxyurea

BACKGROUND: We aimed to clarify the emerging epigenetic landscape in a group of genes classified as “modifier genes” of the β-type globin genes (HBB cluster), known to operate in trans to accomplish the two natural developmental switches in globin expression, from embryonic to fetal during the first...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chondrou, Vasiliki, Stavrou, Eleana F., Markopoulos, Georgios, Kouraklis-Symeonidis, Alexandra, Fotopoulos, Vasilios, Symeonidis, Argiris, Vlachaki, Efthymia, Chalkia, Panagiota, Patrinos, George P., Papachatzopoulou, Adamantia, Sgourou, Argyro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167880/ https://www.ncbi.nlm.nih.gov/pubmed/30285874 http://dx.doi.org/10.1186/s40246-018-0177-z

Ejemplares similares

The multi-faceted functioning portrait of LRF/ZBTB7A
por: Constantinou, Caterina, et al.
Publicado: (2019)

Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients
por: Chondrou, Vasiliki, et al.
Publicado: (2017)

Contingent Synergistic Interactions between Non-Coding RNAs and DNA-Modifying Enzymes in Myelodysplastic Syndromes
por: Symeonidis, Argiris, et al.
Publicado: (2022)

Association of genome variations in the renin-angiotensin system with physical performance
por: Sgourou, Argyro, et al.
Publicado: (2012)

Transcriptional repression of lncRNA and miRNA subsets mediated by LRF during erythropoiesis
por: Athanasopoulou, Katerina, et al.
Publicado: (2023)

Genome-wide analysis toward the epigenetic aetiology of myelodysplastic syndrome disease progression and pharmacoepigenomic basis of hypomethylating agents drug treatment response
por: Siamoglou, Stavroula, et al.
Publicado: (2023)

Editorial: Hybrid or mixed myelodyplastic/myeloproliferative disorders: Current trends in diagnosis and treatment
por: Symeonidis, Argiris, et al.
Publicado: (2023)

Analgesic effect of paracetamol monotherapy vs. the combination of paracetamol/parecoxib vs. the combination of pethidine/paracetamol in patients undergoing thyroidectomy
por: Mulita, Francesk, et al.
Publicado: (2021)

LRF Promotes Indirectly Advantageous Chromatin Conformation via BGLT3-lncRNA Expression and Switch from Fetal to Adult Hemoglobin
por: Chondrou, Vasiliki, et al.
Publicado: (2022)

Non-Viral Episomal Vector Mediates Efficient Gene Transfer of the β-Globin Gene into K562 and Human Haematopoietic Progenitor Cells
por: Lazaris, Vassileios M., et al.
Publicado: (2023)

PB2551: GAUCHER DISEASE CURRICULUM: INCORPORATING GAUCHER DISEASE IN THE FIELD OF HEMATOLOGY
por: Symeonidis, Argiris, et al.
Publicado: (2023)

Chronic Neutrophilic Leukemia: A Comprehensive Review of Clinical Characteristics, Genetic Landscape and Management
por: Thomopoulos, Thomas P., et al.
Publicado: (2022)

Choroidal Thickness Evaluation in a Transfusion-Dependent Beta-Thalassemia Greek Population
por: Tsapardoni, Foteini, et al.
Publicado: (2020)

The Lipoprotein Transport System in the Pathogenesis of Multiple Myeloma: Advances and Challenges
por: Lazaris, Vasileios, et al.
Publicado: (2021)

The incidence of myelodysplastic syndromes in Western Greece is increasing
por: Avgerinou, Christina, et al.
Publicado: (2013)

Allogeneic Hematopoietic Stem Cell Transplantation for Mixed or Overlap Myelodysplastic/Myeloproliferative Disorders
por: Symeonidis, Argiris, et al.
Publicado: (2022)

Bone Marrow Immune Microenvironment in Myelodysplastic Syndromes
por: Kouroukli, Olga, et al.
Publicado: (2022)

P1506: REAL-WORLD DATA ON THE USE OF LUSPATERCEPT IN GREEK PATIENTS WITH TRANSFUSION DEPENDENT THALASSEMIA
por: Delaporta, P., et al.
Publicado: (2022)

High Frequency of Post-Transfusion Microchimerism Among Multi-Transfused Beta-Thalassemic Patients
por: Matsagos, Spyridon, et al.
Publicado: (2022)

Surgical management of hallux valgus and hallux rigidus: an email survey among Swiss orthopaedic surgeons regarding their current practice
por: Iselin, Lukas Daniel, et al.
Publicado: (2015)

Obstructive lower urinary tract symptoms (LUTS) as the initial presentation of penile paraffinoma: a case report and literature review
por: Symeonidis, Asterios, et al.
Publicado: (2021)

P1606: PRIMARY AND SECONDARY IMMUNE THROMBOCYTOPENIA (ITP) IN ADULTS: REAL WORLD COMPARATIVE RETROSPECTIVE STUDY FROM THE ITP REGISTRY OF THE HELLENIC SOCIETY OF HEMATOLOGY
por: Stavroulaki, Emily, et al.
Publicado: (2023)

BTB/POZ zinc finger protein ZBTB16 inhibits breast cancer proliferation and metastasis through upregulating ZBTB28 and antagonizing BCL6/ZBTB27
por: He, Jin, et al.
Publicado: (2020)

Successful Outcome of Chronic Intrahepatic Cholestasis in an Adult Patient with Sickle Cell/β (+) Thalassemia
por: Vlachaki, Efthymia, et al.
Publicado: (2014)

Urothelial neoplasm in a 19‐year‐old male patient with urine discoloration, negative lab, and imaging workup: Should we investigate the findings or the symptom?
por: Symeonidis, Evangelos N., et al.
Publicado: (2019)

ZBTB38 is dispensable for antibody responses
por: Wong, Rachel, et al.
Publicado: (2020)

Matrix and tensor factorization techniques for recommender systems
por: Symeonidis, Panagiotis, et al.
Publicado: (2017)

Techniques and Current Role of Sentinel Lymph Node (SLN) Concept in Gastric Cancer Surgery
por: Symeonidis, Dimitrios, et al.
Publicado: (2019)

Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding
por: Psarras, Kyriakos, et al.
Publicado: (2014)

Bacterial Cellulose Production Using the Corinthian Currant Finishing Side-Stream and Cheese Whey: Process Optimization and Textural Characterization
por: Bekatorou, Argyro, et al.
Publicado: (2019)

Vesicouterine Fistula (VUF) as a Rare Urogenital Complication Managed with Delayed Surgical Repair: A Case Report and Review of the Literature
por: Symeonidis, Evangelos N., et al.
Publicado: (2018)

P1455: THROMBOEMBOLIC EVENTS IN SPLENECTOMISED VERSUS NON-SPLENECTOMISED THALASSEMIA PATIENTS: A META-ANALYSIS OF OBSERVATIONAL STUDIES
por: Vasileia Kalamara, Tsampika, et al.
Publicado: (2023)

Splenectomy is significantly associated with thrombosis but not with pulmonary hypertension in patients with transfusion-dependent thalassemia: a meta-analysis of observational studies
por: Kalamara, Tsampika-Vasileia, et al.
Publicado: (2023)

ZBTB1 is a determinant of lymphoid development
por: Siggs, Owen M., et al.
Publicado: (2012)

Characterization of the ZBTB42 gene in humans and mice
por: Devaney, Stephanie A., et al.
Publicado: (2010)

Hydroxyurea Induced Perimalleolar Ulcers
por: Saravu, Kavitha, et al.
Publicado: (2006)

Mutagenic and Genotoxic Effect of Hydroxyurea
por: Santos, Jean L., et al.
Publicado: (2011)

Blue Lunula Related with Hydroxyurea
por: Üsküdar Teke, Hava, et al.
Publicado: (2013)

The Cell Killing Mechanisms of Hydroxyurea
por: Singh, Amanpreet, et al.
Publicado: (2016)

Hydroxyurea-induced Tooth Discoloration
por: Okuyucu, Muhammed, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0eqjv77955auq820i3tephbrra