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Uncovering new disease indications for G-protein coupled receptors and their endogenous ligands

BACKGROUND: The Open Targets Platform integrates different data sources in order to facilitate identification of potential therapeutic drug targets to treat human diseases. It currently provides evidence for nearly 2.6 million potential target-disease pairs. G-protein coupled receptors are a drug ta...

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Detalles Bibliográficos
Autores principales: Freudenberg, Johannes M, Dunham, Ian, Sanseau, Philippe, Rajpal, Deepak K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167889/
https://www.ncbi.nlm.nih.gov/pubmed/30285606
http://dx.doi.org/10.1186/s12859-018-2392-y