Promiscuous antibodies characterised by their physico-chemical properties: From sequence to structure and back

Human B cells produce antibodies, which bind to their cognate antigen based on distinct molecular properties of the antibody CDR loop. We have analysed a set of 10 antibodies showing a clear difference in their binding properties to a panel of antigens, resulting in two subsets of antibodies with a...

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Detalles Bibliográficos
Autores principales: Laffy, Julie M.J., Dodev, Tihomir, Macpherson, Jamie A., Townsend, Catherine, Lu, Hui Chun, Dunn-Walters, Deborah, Fraternali, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167913/
https://www.ncbi.nlm.nih.gov/pubmed/27639634
http://dx.doi.org/10.1016/j.pbiomolbio.2016.09.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167913/
https://www.ncbi.nlm.nih.gov/pubmed/27639634
http://dx.doi.org/10.1016/j.pbiomolbio.2016.09.002

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