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Promiscuous antibodies characterised by their physico-chemical properties: From sequence to structure and back
Human B cells produce antibodies, which bind to their cognate antigen based on distinct molecular properties of the antibody CDR loop. We have analysed a set of 10 antibodies showing a clear difference in their binding properties to a panel of antigens, resulting in two subsets of antibodies with a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Pergamon Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167913/ https://www.ncbi.nlm.nih.gov/pubmed/27639634 http://dx.doi.org/10.1016/j.pbiomolbio.2016.09.002 |