Genome mining, isolation, chemical synthesis and biological evaluation of a novel lanthipeptide, tikitericin, from the extremophilic microorganism Thermogemmatispora strain T81

Genome mining of the New Zealand extremophilic microorganism Thermogemmatispora strain T81 indicated the presence of biosynthetic machinery to produce several different peptidic natural products. Solid-phase culture of T81 led to the isolation of tikitericin 1, a new lanthipeptide characterised by f...

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Detalles Bibliográficos
Autores principales: Xu, Buzhe, Aitken, Emma J., Baker, Benjamin P., Turner, Claire A., Harvey, Joanne E., Stott, Matthew B., Power, Jean F., Harris, Paul W. R., Keyzers, Robert A., Brimble, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167946/
https://www.ncbi.nlm.nih.gov/pubmed/30294420
http://dx.doi.org/10.1039/c8sc02170h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167946/
https://www.ncbi.nlm.nih.gov/pubmed/30294420
http://dx.doi.org/10.1039/c8sc02170h

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