Suppression of testosterone production by nanoparticulate TiO(2) is associated with ERK1/2–PKA–PKC signaling pathways in rat primary cultured Leydig cells

BACKGROUND: Nanoparticulate titanium dioxide (nano-TiO(2)) enters the body through various routes and causes organ damage. Exposure to nano-TiO(2) is reported to cause testicular injury in mice or rats and decrease testosterone synthesis, sperm number, and motility. Importantly, nano-TiO(2) suppress...

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Detalles Bibliográficos
Autores principales: Li, Lingjuan, Mu, Xu, Ye, Lingqun, Ze, Yuguan, Hong, Fashui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167999/
https://www.ncbi.nlm.nih.gov/pubmed/30319256
http://dx.doi.org/10.2147/IJN.S175608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167999/
https://www.ncbi.nlm.nih.gov/pubmed/30319256
http://dx.doi.org/10.2147/IJN.S175608

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