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Suppression of testosterone production by nanoparticulate TiO(2) is associated with ERK1/2–PKA–PKC signaling pathways in rat primary cultured Leydig cells
BACKGROUND: Nanoparticulate titanium dioxide (nano-TiO(2)) enters the body through various routes and causes organ damage. Exposure to nano-TiO(2) is reported to cause testicular injury in mice or rats and decrease testosterone synthesis, sperm number, and motility. Importantly, nano-TiO(2) suppress...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167999/ https://www.ncbi.nlm.nih.gov/pubmed/30319256 http://dx.doi.org/10.2147/IJN.S175608 |