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Network, Transcriptomic and Genomic Features Differentiate Genes Relevant for Drug Response

Understanding the mechanisms underlying drug therapeutic action and toxicity is crucial for the prevention and management of drug adverse reactions, and paves the way for a more efficient and rational drug design. The characterization of drug targets, drug metabolism proteins, and proteins associate...

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Detalles Bibliográficos
Autores principales: Piñero, Janet, Gonzalez-Perez, Abel, Guney, Emre, Aguirre-Plans, Joaquim, Sanz, Ferran, Oliva, Baldo, Furlong, Laura I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168038/
https://www.ncbi.nlm.nih.gov/pubmed/30319692
http://dx.doi.org/10.3389/fgene.2018.00412