Duplex Proximity Sequencing (Pro-Seq): A method to improve DNA sequencing accuracy without the cost of molecular barcoding redundancy

A challenge in the clinical adoption of cell-free DNA (cfDNA) liquid biopsies for cancer care is their high cost compared to potential reimbursement. The most common approach used in liquid biopsies to achieve high specificity detection of circulating tumor DNA (ctDNA) among a large background of no...

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Detalles Bibliográficos
Autores principales: Pel, Joel, Choi, Wendy W. Y., Leung, Amy, Shibahara, Gosuke, Gelinas, Laura, Despotovic, Milenko, Ung, W. Lloyd, Marziali, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168144/
https://www.ncbi.nlm.nih.gov/pubmed/30278055
http://dx.doi.org/10.1371/journal.pone.0204265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168144/
https://www.ncbi.nlm.nih.gov/pubmed/30278055
http://dx.doi.org/10.1371/journal.pone.0204265

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