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Transition state characteristics during cell differentiation

Models describing the process of stem-cell differentiation are plentiful, and may offer insights into the underlying mechanisms and experimentally observed behaviour. Waddington’s epigenetic landscape has been providing a conceptual framework for differentiation processes since its inception. It als...

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Detalles Bibliográficos
Autores principales: Brackston, Rowan D., Lakatos, Eszter, Stumpf, Michael P. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168170/
https://www.ncbi.nlm.nih.gov/pubmed/30235202
http://dx.doi.org/10.1371/journal.pcbi.1006405