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Determinants of selective ion permeation in the epithelial Na(+) channel

The epithelial Na(+) channel (ENaC) is a key transporter mediating and controlling Na(+) reabsorption in many tight epithelia. A very high selectivity for Na(+) over other cations, including K(+), is a hallmark of this channel. This selectivity greatly exceeds that of the closely related acid-sensin...

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Detalles Bibliográficos
Autores principales: Yang, Lei, Palmer, Lawrence G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168236/
https://www.ncbi.nlm.nih.gov/pubmed/30135076
http://dx.doi.org/10.1085/jgp.201812164