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A novel in vitro assay reveals SNARE topology and the role of Ykt6 in autophagosome fusion with vacuoles
Autophagy is a catabolic pathway that delivers intracellular material to the mammalian lysosomes or the yeast and plant vacuoles. The final step in this process is the fusion of autophagosomes with vacuoles, which requires SNARE proteins, the homotypic vacuole fusion and protein sorting tethering co...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168247/ https://www.ncbi.nlm.nih.gov/pubmed/30097515 http://dx.doi.org/10.1083/jcb.201804039 |