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A novel in vitro assay reveals SNARE topology and the role of Ykt6 in autophagosome fusion with vacuoles

Autophagy is a catabolic pathway that delivers intracellular material to the mammalian lysosomes or the yeast and plant vacuoles. The final step in this process is the fusion of autophagosomes with vacuoles, which requires SNARE proteins, the homotypic vacuole fusion and protein sorting tethering co...

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Detalles Bibliográficos
Autores principales: Gao, Jieqiong, Reggiori, Fulvio, Ungermann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168247/
https://www.ncbi.nlm.nih.gov/pubmed/30097515
http://dx.doi.org/10.1083/jcb.201804039