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Reconstitution reveals Ykt6 as the autophagosomal SNARE in autophagosome–vacuole fusion
Autophagy mediates the bulk degradation of cytoplasmic material, particularly during starvation. Upon the induction of autophagy, autophagosomes form a sealed membrane around cargo, fuse with a lytic compartment, and release the cargo for degradation. The mechanism of autophagosome–vacuole fusion is...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168255/ https://www.ncbi.nlm.nih.gov/pubmed/30097514 http://dx.doi.org/10.1083/jcb.201804028 |