Pink1/Parkin link inflammation, mitochondrial stress, and neurodegeneration

What causes inflammation in age-related neurodegenerative diseases remains a mystery. Sliter et al. (2018. Nature. https://doi.org/10.1038/s41586-018-0448-9) show that, when damaged mitochondria cannot be removed by mitophagy, stress from exercise or mitochondrial DNA mutations activates the proinfl...

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Detalles Bibliográficos
Autores principales: Newman, Laura E., Shadel, Gerald S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168260/
https://www.ncbi.nlm.nih.gov/pubmed/30154188
http://dx.doi.org/10.1083/jcb.201808118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168260/
https://www.ncbi.nlm.nih.gov/pubmed/30154188
http://dx.doi.org/10.1083/jcb.201808118

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