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Pink1/Parkin link inflammation, mitochondrial stress, and neurodegeneration
What causes inflammation in age-related neurodegenerative diseases remains a mystery. Sliter et al. (2018. Nature. https://doi.org/10.1038/s41586-018-0448-9) show that, when damaged mitochondria cannot be removed by mitophagy, stress from exercise or mitochondrial DNA mutations activates the proinfl...
Autores principales: | Newman, Laura E., Shadel, Gerald S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168260/ https://www.ncbi.nlm.nih.gov/pubmed/30154188 http://dx.doi.org/10.1083/jcb.201808118 |
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