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The inositol 5-phosphatase INPP5K participates in the fine control of ER organization

INPP5K (SKIP) is an inositol 5-phosphatase that localizes in part to the endoplasmic reticulum (ER). We show that recruitment of INPP5K to the ER is mediated by ARL6IP1, which shares features of ER-shaping proteins. Like ARL6IP1, INPP5K is preferentially localized in ER tubules and enriched, relativ...

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Detalles Bibliográficos
Autores principales: Dong, Rui, Zhu, Ting, Benedetti, Lorena, Gowrishankar, Swetha, Deng, Huichao, Cai, Yiying, Wang, Xiangming, Shen, Kang, De Camilli, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168264/
https://www.ncbi.nlm.nih.gov/pubmed/30087126
http://dx.doi.org/10.1083/jcb.201802125