Chromosome structural anomalies due to aberrant spindle forces exerted at gene editing sites in meiosis

Mouse female meiotic spindles assemble from acentriolar microtubule-organizing centers (aMTOCs) that fragment into discrete foci. These are further sorted and clustered to form spindle poles, thus providing balanced forces for faithful chromosome segregation. To assess the impact of aMTOC biogenesis...

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Detalles Bibliográficos
Autores principales: Manil-Ségalen, Marion, Łuksza, Małgorzata, Kanaan, Joanne, Marthiens, Véronique, Lane, Simon I.R., Jones, Keith T., Terret, Marie-Emilie, Basto, Renata, Verlhac, Marie-Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168266/
https://www.ncbi.nlm.nih.gov/pubmed/30082296
http://dx.doi.org/10.1083/jcb.201806072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168266/
https://www.ncbi.nlm.nih.gov/pubmed/30082296
http://dx.doi.org/10.1083/jcb.201806072

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