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A quantitative analysis of cohesin decay in mitotic fidelity

Sister chromatid cohesion mediated by cohesin is essential for mitotic fidelity. It counteracts spindle forces to prevent premature chromatid individualization and random genome segregation. However, it is unclear what effects a partial decline of cohesin may have on chromosome organization. In this...

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Detalles Bibliográficos
Autores principales: Carvalhal, Sara, Tavares, Alexandra, Santos, Mariana B., Mirkovic, Mihailo, Oliveira, Raquel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168270/
https://www.ncbi.nlm.nih.gov/pubmed/30002073
http://dx.doi.org/10.1083/jcb.201801111