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Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture

Dynamin-related proteins (DRPs) are large multidomain GTPases required for diverse membrane-remodeling events. DRPs self-assemble into helical structures, but how these structures are tailored to their cellular targets remains unclear. We demonstrate that the fungal DRP Vps1 primarily localizes to a...

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Detalles Bibliográficos
Autores principales: Varlakhanova, Natalia V., Alvarez, Frances J.D., Brady, Tyler M., Tornabene, Bryan A., Hosford, Christopher J., Chappie, Joshua S., Zhang, Peijun, Ford, Marijn G.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168280/
https://www.ncbi.nlm.nih.gov/pubmed/30087125
http://dx.doi.org/10.1083/jcb.201712021