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Metabolism of a synthetic compared with a natural therapeutic pulmonary surfactant in adult mice

Secreted pulmonary surfactant phosphatidylcholine (PC) has a complex intra-alveolar metabolism that involves uptake and recycling by alveolar type II epithelial cells, catabolism by alveolar macrophages, and loss up the bronchial tree. We compared the in vivo metabolism of animal-derived poractant a...

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Detalles Bibliográficos
Autores principales: Madsen, Jens, Panchal, Madhuriben H., Mackay, Rose-Marie A., Echaide, Mercedes, Koster, Grielof, Aquino, Giancarlo, Pelizzi, Nicola, Perez-Gil, Jesus, Salomone, Fabrizio, Clark, Howard W., Postle, Anthony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168297/
https://www.ncbi.nlm.nih.gov/pubmed/30108154
http://dx.doi.org/10.1194/jlr.M085431