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Metabolism of a synthetic compared with a natural therapeutic pulmonary surfactant in adult mice
Secreted pulmonary surfactant phosphatidylcholine (PC) has a complex intra-alveolar metabolism that involves uptake and recycling by alveolar type II epithelial cells, catabolism by alveolar macrophages, and loss up the bronchial tree. We compared the in vivo metabolism of animal-derived poractant a...
Autores principales: | Madsen, Jens, Panchal, Madhuriben H., Mackay, Rose-Marie A., Echaide, Mercedes, Koster, Grielof, Aquino, Giancarlo, Pelizzi, Nicola, Perez-Gil, Jesus, Salomone, Fabrizio, Clark, Howard W., Postle, Anthony D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168297/ https://www.ncbi.nlm.nih.gov/pubmed/30108154 http://dx.doi.org/10.1194/jlr.M085431 |
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