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Global genetic diversity of human apolipoproteins and effects on cardiovascular disease risk

Abnormal plasma apolipoprotein levels are consistently implicated in CVD risk. Although 30% to 60% of their interindividual variability is genetic, common genetic variants explain only 10% to 20% of these differences. Rare genetic variants may be major sources of the missing heritability, yet quanti...

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Detalles Bibliográficos
Autores principales: Zhou, Yitian, Mägi, Reedik, Milani, Lili, Lauschke, Volker M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168301/
https://www.ncbi.nlm.nih.gov/pubmed/30076208
http://dx.doi.org/10.1194/jlr.P086710