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Baricitinib-induced blockade of interferon gamma receptor and interleukin-6 receptor for the prevention and treatment of graft-versus-host disease

The therapeutic benefits of allogeneic hematopoietic stem cell transplantation (allo-HSCT) are derived from the graft-versus-leukemia (GvL) effects of the procedure. There is a strong association between the GvL effects and graft-versus-host disease (GvHD), a major life-threatening complication of a...

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Detalles Bibliográficos
Autores principales: Choi, Jaebok, Cooper, Matthew L., Staser, Karl, Ashami, Kidist, Vij, Kiran R., Wang, Bing, Marsala, Lynne, Niswonger, Jessica, Ritchey, Julie, Alahmari, Bader, Achilefu, Samuel, Tsunoda, Ikuo, Schroeder, Mark A., DiPersio, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168427/
https://www.ncbi.nlm.nih.gov/pubmed/29691471
http://dx.doi.org/10.1038/s41375-018-0123-z