Simvastatin Protects Cardiomyocytes Against Endotoxin-induced Apoptosis and Up-regulates Survivin/NF-κB/p65 Expression

This study is aimed to investigate whether simvastatin induces cardiomyocytes survival signaling in endotoxin (lipopolysaccharide, LSP)-induced myocardial injury, and if so, further to determine a role of survivin in simvastatin-anti-apoptotic effect. Wistar rats were pretreated with simvastatin (10...

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Detalles Bibliográficos
Autores principales: Nežić, Lana, Škrbić, Ranko, Amidžić, Ljiljana, Gajanin, Radoslav, Kuča, Kamil, Jaćević, Vesna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168467/
https://www.ncbi.nlm.nih.gov/pubmed/30279549
http://dx.doi.org/10.1038/s41598-018-32376-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168467/
https://www.ncbi.nlm.nih.gov/pubmed/30279549
http://dx.doi.org/10.1038/s41598-018-32376-4

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