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Sin3A recruits Tet1 to the PAH1 domain via a highly conserved Sin3-Interaction Domain

The Sin3A complex acts as a transcriptional hub, integrating the function of diverse transcription factors with histone modifying enzymes, notably, histone deacetylases (HDAC) 1 and 2. The Sin3A protein sits at the centre of the complex, mediating multiple simultaneous protein-protein interactions v...

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Detalles Bibliográficos
Autores principales: Chandru, Aditya, Bate, Neil, Vuister, Geerten W., Cowley, Shaun M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168491/
https://www.ncbi.nlm.nih.gov/pubmed/30279502
http://dx.doi.org/10.1038/s41598-018-32942-w